Aspiring rock musician Neal Downs manages a cereal bar. Stylish Miss Pussy Katz is the creator of radically-themed art clothing. When the cereal bar, brings in an offbeat crew of locals, who debate the arcana of cereal history and ideal milk/flake ratios, an aspiring capitalist rips off their concept.

Upon hearing of her mother's death, jaded teenage loner Purslane Hominy Will returns to New Orleans for the first time in years, ready to reclaim her childhood home. Expecting to find her late mother's house abandoned, Pursy is shocked to discover that it is inhabited by two of her mother's friends: Bobby Long, a former literature professor, and his young protégé, Lawson Pines. These broken men, whose lives took a wrong turn years before, have been firmly rooted in the dilapidated house for years, encouraged only by Lawson's faltering ambitions to write a novel about Bobby Long's life. Having no intention of leaving, Pursy, Bobby Long and Lawson are all forced to live together. Yet as time passes, their tenuous, makeshift arrangement unearths a series of buried personal secrets that challenges their bonds, and reveals just how inextricably their lives are intertwined.

Lt. Dave Robicheaux, a detective in New Iberia, Louisiana, is trying to link the murder of a local hooker to New Orleans mobster Julie (Baby Feet) Balboni, who is co-producer of a Civil War film. At the same time, after Elrod Sykes, the star of the film, reports finding another corpse in the Atchafalaya Swamp near the movie set, Robicheaux starts another investigation, believing the corpse to be the remains of a black man who he saw being murdered 35 years before.